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Flash Chromatography Purification

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Flash Chromatography Model 420 Specs:

  • chromatography column capacities range from 4 to 800g.
  • able to pump the mobile phase from 5-300 ml./min. into the column or stationary phase – (at a max of 20 bar)
  • compact – (13.9” x 18.5” x 29.5”) W x L x H
  • UV Diode Array Detector – with 200-400 nm range

Flash Chromatography Model 800 Specs:

  • chromatography column capacities range from 4 to 4,500g.
  • able to pump the mobile phase from 5-300 ml./min. into the column or stationary phase – (at a max of 7 bar)
  • allows for unlimited collection via its four funnel racks – (instead of having to use test tube racks)
  • UV Diode Array Detector – with 400 or 840 nm. range

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Unlike traditional column chromatography glassware, these flash chromatography units are automated and use pressure and force on your sample through the column (which is already packed with packing material).

As the mobile phase works through the column, it will only pull out certain molecules, while leaving others behind (due to how closely the solvents match the molecules’ polarity).

Faster, easier, and way more efficient.

These machines represent a tremendous advantage over column chromatography, in part because they have a digital read out from the built-in UV detector, which allows you to see what peaks are being produced. This readout lets you see what’s eluting or coming out of your column first. This way you can separate what you want more efficiently than ever before.

Sometimes referred to as low-pressure liquid chromatography, flash chromatography auto deposits samples into the machine. If you used traditional glass, on the other hand, you would have to sit there and move test tubes each time one filled up, wasting time.

Accurate & reliable – welcome to the future.

You can purify synthesis reaction mixtures, proteins, peptides, and natural extracts – from milligram to gram quantities.

The Iquat Gradient HPLC pump has a 1% accuracy, making for an efficient mixture of gradients within the unit.

You can also avoid “pre-mixing” the mobile phase with this machine.


  • two models available: 420 & 800
  • accepts varying size collection tubes – You can select the correct volume and size for your runs.
  • accepts flash chromatography columns from F0001 up to F0330, as well as prep LC columns (depending on model chosen)
  • UV Diode Array Detector – for accurate and repeatable results (with respect to compound peaks) while performing a run
  • multiple collection racks
  • full, touch-screen display

Not only that, but during a run, the instrument will generate a chromatogram for use in recognizing retention time and concentration of compounds against known standards

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